Current Issue : January-March Volume : 2021 Issue Number : 1 Articles : 2 Articles
Psoriasis is a persistent inflammatory and immune-mediated skin disease in which skin cells build up 10 times faster than normal and form plaques, silvery patches and dry skin and it affects 2-3% of the total population throughout the world. Many hereditary or environmental factors triggered the activation of several pro-inflammatory cytokines; such as tumor necrosis factor (TNF)-a, interferon (IFN) and interleukin (IL). It is associated with many simultaneous co-morbidities including cardiovascular diseases (arteriosclerosis, myocardial infarction and hypertension), metabolic diseases (obesity, insulin resistance and dyslipidemia), joint disorders (psoriatic arthritis, osteoporosis) and psychological problems (anxiety and depression). These comorbidities make the disease the main health concern that needs the assistance of dermatologists and other health care specialists. The topical agents and phototherapy used for psoriasis patients. Even though these methods are beneficial only for symptomatic efficient relief of skin lesions but not have an effect on primary causes of disease. This review summarizes the clinical manifestations, diagnosis, pathophysiological links and relationship that associate with psoriasis and common comorbidities and highlights the treatment strategies to control systemic inflammation and could diminish the concerns of related disorders in the future....
Regenerative property of skin makes it primary organ that provides protection of underlying muscles, bones, ligaments and internal organ from any external biological, chemical and physical agents. Additionally, skin also helps in temperature regulation, dehydration, synthesis of vitamin D3. A wound is considered as a disturbance in the continuation of epithelial lining of skin or mucosa resulting from physical or thermal damage. Depending on the nature of healing process and duration wound is classified as acute and chronic and chronic wounds have a severe impact on health and quality of life that lead many difficulties like causing pain, loss of function, depression, anxiety, long term hospitalization and chronic morbidity and death. Therefore, appropriate wound care is necessary to prevent infection and further complications. In this review paper discussion is about recent advances in antimicrobial dressing which is used for both wound healing of acute and chronic wounds. This review article deals with wound and its types along with its pathophysiology, polymers used in wound dressing, Patents and commercially available wound dressing....
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